VIB spin-off MRM Health reports positive preclinical results in non-alcoholic fatty liver disease

MRM Health is a VIB spin-off founded in 2020 by Sam Possemiers in a joint venture with VIB. Using a 9-strain bacterial consortium, MRM Health’s laboratories led by Dr. Salvador Augustin and Dr. Maria Martell of the University Hospital of Vall d’Hebron were able to slow down disease progression in Non-Alcoholic Fatty Liver Disease (NAFLD). Preclinical results show that a live bacterial consortium of 9 rationally selected gut commensal strains were able to improve portal hypertension, insulin signaling, and NAFLD activity score. Additionally, the consortium helped prevent fibrosis development in two different in vivo disease models of Non-Alcoholic Steatohepatitis (NASH), improving endothelial functions and rebalancing the gut microbiome.


Lies Vanneste

Lies Vanneste

Investor Relations Manager, VIB

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VIB is an independent research institute that translates insights in biology into impactful innovations for society. Collaborating with the five Flemish universities, it conducts research in plant biology, cancer, neuroscience, microbiology, inflammatory diseases, artificial intelligence and more. VIB connects science with entrepreneurship and stimulates the growth of the Flemish biotech ecosystem. The institute contributes to solutions for societal challenges such as new methods for diagnostics and treatments, as well as innovations for agriculture. 

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