What causes cancer and how can we find better ways to treat it?
Researchers map cell composition of metastatic melanoma and identify cause of immunotherapy resistance
Targeting mesenchymal-like melanoma cells could instigate immunotherapy response
January 9, 2024
Researchers discover that disabling autophagy in Tumor Endothelial Cells, inflames them and leads to a better immune response
November 28, 2023
Fucosylation – the addition of a fucose sugar to a molecule – has been identified as the driving force behind unbalanced Treg behavior in tumor microenvironment
November 13, 2023
Tracer metabolomics reveals the role of aldose reductase in glycosylation
June 5, 2023
TRAIL proteins function as gatekeepers for vascular barrier integrity and blocks entry of cancer cells to metastatic sites
March 23, 2023
Palmitate can initiate a series of signals in cancer cells that equip them to grow into metastases.
February 3, 2023
Inhibiting the bicarbonate transporter SLC4A4 in pancreatic cancer cells promotes an immune reaction and supports immunotherapy effectiveness.
December 15, 2022
Therapeutic induction of High-Endothelial Venules (HEV) can augment lymphocyte infiltration and contributes to tumor growth inhibition
November 24, 2022
VIB researchers uncover a metabolic switch that allows immune cells to enhance their protective function.
November 17, 2022
New discoveries open new avenues for the prevention of early tumor growth and metastatic dissemination
September 22, 2022
Training our immune system to recognize and attack tumors – immunotherapy – holds great promise for cancer therapy. New research by scientists from VIB, VUB, UGent, KU Leuven, and international partner Roche now shows why some patients don’t respond to immunotherapy. By clarifying the role of different cell types involved in the immune system’s response, this work by the team of Prof. Damya Laoui is an important step toward personalized treatment for cancer patients and is published in Cancer Research.
August 18, 2022