Cancer Biology

Groundbreaking Study Offers a Novel Approach to Enhance Neuromuscular Function in Patients with Duchenne Muscular Dystrophy

Findings published in The American Journal of Pathology identify GLUD1 enzyme as a potential therapeutic target for muscle restoration through metabolic reprogramming, addressing clinically unmet need for treatment beyond symptom relief

Researchers uncover surprising role of 'natural killer' cells in resistance to cancer immunotherapy

Targeting NK cells could open the door to more effective immunotherapy in resistant tumors

Killing cancer cells by boosting organelle bridges

Endoplasmic reticulum-mitochondria contact sites drive ferroptosis

Improving melanoma treatment by blocking an enzyme

Study shows HPGDS plays a key role in immunotherapy resistance

Reprogramming immune cells to improve cancer treatment

Scientists at the VIB-KU Leuven Center for Cancer Biology and their collaborators demonstrated a remarkable ability to boost the immune system's fight against cancer

Researchers reveal why the lung is a frequent site of cancer metastasis

The availability of the amino acid aspartate is one reason why the lung is a frequent organ of metastasis

Does the menstrual cycle influence the effect of chemotherapy?

Researchers call for more women-specific drug research

Scientists discover how specific E. coli bacteria drive colon cancer

Certain E. coli bacteria in the gut promote colon cancer by binding to intestinal cells and releasing a DNA-damaging toxin

Menstrual cycle influences the spread of mutant cells in mammary tissue  

Researchers identify a key metabolic gene as target for improved cancer immunotherapy

The CDA gene is among the top upregulated metabolic genes in immunotherapy-resistant tumors

Researchers map cell composition of metastatic melanoma and identify cause of immunotherapy resistance

Targeting mesenchymal-like melanoma cells could instigate immunotherapy response

Disabling autophagy can enhance immune response in melanoma

Researchers discover that disabling autophagy in Tumor Endothelial Cells, inflames them and leads to a better immune response