Immunity & Inflammation

The science behind our bodies' defense lines

Newly discovered protein blocks sleeping sickness 

Newly discovered protein blocks sleeping sickness 

New research by the lab of Prof. Jo Van Ginderachter (VIB Center for Inflammation Research and VUB), in collaboration with Prof. Carl De Trez (VUB) and others, identifies a protein that could pave the way toward drugs against sleeping sickness.

February 28, 2024

Erosion blockade breakthrough: clinical trial signals hope for hand osteoarthritis

Erosion blockade breakthrough: clinical trial signals hope for hand osteoarthritis

Researchers at the Ghent University Hospital, Ghent University, and VIB-UGent Center for Inflammation Research, show that antibody therapy can be effective against erosive hand osteoarthritis. Using the antibody denosumab leads to bone remodeling and the prevention of erosive joint damage. This is the first evidence that erosive progression can be halted in this disease. The results appear in Nature Medicine.

February 15, 2024

From goblet cells to gut health: the role of AGR2 and mucus

From goblet cells to gut health: the role of AGR2 and mucus

The AGR2 protein plays a pivotal role in regulating intestinal mucus production through its interaction with IRE1β, revealing a crucial mechanism for maintaining a healthy gut environment

January 8, 2024

Untangling gut and joint inflammation in arthritis 

Untangling gut and joint inflammation in arthritis 

New study reveals distinct triggers for gut and joint inflammation using germ-free mouse technology.  

September 11, 2023

AI assists in arthritis diagnosis based on MRI images 

AI assists in arthritis diagnosis based on MRI images 

A fully automated machine learning algorithm predicts bone marrow inflammation in MRI scans

August 28, 2023

Immune system causes lung damage in COVID patients

Immune system causes lung damage in COVID patients

Inflammatory agent Interleukin-6 fires up complement system

August 24, 2023

New study challenges prevailing theory of liposomal accumulation and improves drug delivery to inflamed tissues

New study challenges prevailing theory of liposomal accumulation and improves drug delivery to inflamed tissues

Study reveals that myeloid cells play a crucial role in the accumulation of liposomes in inflamed tissues

July 12, 2023

Researchers reveal a crucial process in the working of the immune system

Researchers reveal a crucial process in the working of the immune system

VIB researchers show how dendritic cells mature without causing an immune response

May 15, 2023

Decoding the satiety signal

Decoding the satiety signal

Research reveals how leptin and its receptor work together to regulate hunger signals

March 24, 2023

Excess salt cuts energy supply of immune regulators

Excess salt cuts energy supply of immune regulators

Too much salt can disrupt the energy metabolism in regulatory immune cells

February 7, 2023

Scientists discover a new brake on cell death

Scientists discover a new brake on cell death

The protein ATG9A blocks the cell-killing signal of tumor necrosis factor and prevents unwanted cell death

December 19, 2022

Protecting ourselves from herpes: when trash becomes treasure

Protecting ourselves from herpes: when trash becomes treasure

Mutations in a key gene that was thought to be 'junk' DNA are linked to the risk of encephalitis after HSV-1 infection.

November 21, 2022

About VIB

VIB is an independent research institute that translates insights in biology into impactful innovations for society. Collaborating with the five Flemish universities, it conducts research in plant biology, cancer, neuroscience, microbiology, inflammatory diseases, artificial intelligence and more. VIB connects science with entrepreneurship and stimulates the growth of the Flemish biotech ecosystem. The institute contributes to solutions for societal challenges such as new methods for diagnostics and treatments, as well as innovations for agriculture. 

Learn more at www.vib.be.

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