Immunity & Inflammation
The science behind our bodies' defense lines
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Scientists discover how specific E. coli bacteria drive colon cancer
Certain E. coli bacteria in the gut promote colon cancer by binding to intestinal cells and releasing a DNA-damaging toxin
November 7, 2024
Repeated COVID vaccines enhance mucosal immunity against the virus
People who received multiple doses of mRNA vaccines showed more neutralizing antibodies in nasal secretions
October 24, 2024
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Cells that die during inflammation send wound-healing messages
A study by the team of Prof. Kodi Ravichandran (VIB-UGent Center for Inflammation Research) and colleagues found that pyroptosis, a form of programmed cell death traditionally thought to be purely inflammatory, also plays a crucial role in promoting healing and tissue repair. This research, published in Nature, opens new avenues for understanding how our bodies respond to injury and could lead to innovative treatments for wounds and inflammatory diseases.
September 11, 2024
Past infections have long-term effects on liver immune cells
Many infections affect the liver, yet little is known about the long-term impact of these infections on the liver’s immune cells. Now, a study by the teams of Prof. Jo Van Ginderachter (VIB-VUB) and Prof Kiavash Movahedi at VUB reveals long-lasting changes in the liver’s Kupffer cells following an infection. The work appears in the Journal of Hepatology.
July 23, 2024
Newly discovered protein blocks sleeping sickness
New research by the lab of Prof. Jo Van Ginderachter (VIB Center for Inflammation Research and VUB), in collaboration with Prof. Carl De Trez (VUB) and others, identifies a protein that could pave the way toward drugs against sleeping sickness.
February 28, 2024
Erosion blockade breakthrough: clinical trial signals hope for hand osteoarthritis
Researchers at the Ghent University Hospital, Ghent University, and VIB-UGent Center for Inflammation Research, show that antibody therapy can be effective against erosive hand osteoarthritis. Using the antibody denosumab leads to bone remodeling and the prevention of erosive joint damage. This is the first evidence that erosive progression can be halted in this disease. The results appear in Nature Medicine.
February 15, 2024
From goblet cells to gut health: the role of AGR2 and mucus
The AGR2 protein plays a pivotal role in regulating intestinal mucus production through its interaction with IRE1β, revealing a crucial mechanism for maintaining a healthy gut environment
January 8, 2024
Untangling gut and joint inflammation in arthritis
New study reveals distinct triggers for gut and joint inflammation using germ-free mouse technology.
September 11, 2023
AI assists in arthritis diagnosis based on MRI images
A fully automated machine learning algorithm predicts bone marrow inflammation in MRI scans
August 28, 2023
Immune system causes lung damage in COVID patients
Inflammatory agent Interleukin-6 fires up complement system
August 24, 2023
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New study challenges prevailing theory of liposomal accumulation and improves drug delivery to inflamed tissues
Study reveals that myeloid cells play a crucial role in the accumulation of liposomes in inflamed tissues
July 12, 2023
Researchers reveal a crucial process in the working of the immune system
VIB researchers show how dendritic cells mature without causing an immune response
May 15, 2023